Downstream Associate

Sino Biological

Houston, TX 77030


Description

Sino Biological is passionate about empowering life science discovery with high-quality recombinant proteins, antibodies, and comprehensive technical services, all developed and produced in-house. We're proud to serve as a trusted, one-stop partner for researchers around the globe, and we also support pharmaceutical and biotech companies with pre-clinical production services for hundreds of monoclonal antibody drug candidates.

With headquarters in Beijing and a growing global presence, Sino Biological has exciting opportunities waiting for you! We’re hiring across several vibrant locations, including Texas, Paris, London, and Beijing. Join us and be part of a mission-driven team that’s shaping the future of biotech, one breakthrough at a time.


Send your CV to Send your CV to careers@sinobiologicalus.com

About Us
Sino Biological is an internationally recognized reagent supplier and contract research organization, listed on ChiNext of the Shenzhen stock exchange (301047 Sino Biological Inc.). Sino Biological's core technology platform is its in-house developed mammalian cell-based recombinant expression system, which employs proprietary reagents and processes for the efficient production of antigens and antibodies.

With its main manufacturing facilities in Beijing, China, Sino Biological also has a growing global presence with a US headquarters in the greater Philadelphia area, a bioprocessing facility in Houston, Texas, and subsidiaries in Frankfurt, Germany, and Tokyo, Japan. As part of its major global expansion, the company has established the Center for Bioprocessing (C4B) in Houston, Texas, located in the renowned Texas Medical Center at Levit Green. C4B is equipped with state-of-the-art facilities and staffed by a team of experts, driving innovation in bioprocessing.

Job Title: Downstream Associate
Location: Houston, TX

Job Description
This is an entry-level position suitable for individuals seeking hands-on experience in protein purification and quality control in an industrial bioprocessing environment. The Associate will support the downstream team in executing purification workflows and conducting protein characterization assays to evaluate product quality. Responsibilities include chromatography-based purification, recombinant protein QC related tasks under the guidance of project scientists. This role requires strong attention to detail, good lab documentation practices, and effective collaboration with cross-functional teams.

Responsibilities
  • Perform purification of recombinant proteins and antibodies from mammalian expression systems using chromatography methods and equipment (e.g., AKTA systems).

  • Execute established downstream workflows to meet project specifications and client requirements.

  • Conduct protein quality control testing, including SDS-PAGE, HPLC-SEC, endotoxin assays, UV-Vis concentration measurement, and other analytical assays.

  • Support lead scientists in preparing and analyzing QC data and interpreting protein quality results as part of downstream bioprocessing, including purification and quality control.

  • Maintain accurate batch records, lab notebooks, and QC documentation in compliance with internal standards and client requirements.

  • Ensure compliance with laboratory safety protocols and PPE usage in accordance with federal, state, and local regulatory guidelines.

  • Assist with calibration, maintenance, and basic troubleshooting of chromatography and analytical instruments.

  • Collaborate with other teams within the Center to support smooth project coordination and delivery.

  • Requirements
  • Bachelor’s degree in Biology, Biochemistry, Biotechnology, or a related field.

  • 0–3 years of relevant laboratory experience, with basic understanding of protein purification and analytical methods.

  • Familiarity with chromatographic systems such as FPLC or HPLC used for protein purification.

  • Experience or exposure to protein QC analytical assays, such as SDS-PAGE, HPLC-SEC, and endotoxin testing and ELISA.

  • Strong organizational and documentation skills, with attention to detail.

  • Willingness to work a flexible schedule, including early/late weekday shifts and occasional weekend work depending on project needs.

  • Good communication skills and a collaborative team mindset.

  • Flexibility is required, including potential weekend work and early or late weekday shifts based on project demands.

  • Must be able to lift and move 25–50 lbs as needed.

  • Why Join Us?
  • Competitive compensation package.

  • Learn directly from industry professionals in a global biotech company.

  • Career growth opportunities and mentorship.

  • A welcoming, team-first workplace that celebrates diversity and collaboration.

  • Note:
    Only shortlisted candidates will be contacted for interviews. If selected, an HR team member will reach out to schedule a quick phone interview using the contact information provided in your resume.

    Sino Biological Inc. is an equal-opportunity employer. We celebrate diversity and are committed to building an inclusive environment for all employees.

    #LI-Onsite


    Job type: Full-time
    Salary range: Based on qualifications
    Bonus: Based on sales target


    Why Join Us?
    At Sino Biological, we recognize that our people are our greatest asset. That’s why we offer:
  • Competitive compensation packages, including a base salary and a bonus structure plan.

  • Professional development and career advancement opportunities, including an intensive training and rotation program.

  • A supportive and inclusive work environment where diversity is celebrated.


  • Sino Biological is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.
    Join Us in Advancing Scientific Innovation!
    Be a part of Sino Biological and contribute to groundbreaking scientific advancements worldwide. Apply today to join our dynamic team!


    Contact Us:
    careers@sinobiological.com.


    Sino Biological provides an Equal Employment Opportunity. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (sexual orientation, gender identity), age, national origin, disability, or genetic information.

    Interested in this job?

    Apply now

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