Associate Manager, Precision Medicine & Biomarkers

Immatics US

Houston, TX


Description

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!
Immatics is at the forefront of immunotherapy innovation, working to harness the power of T cells to transform cancer treatment.
Immatics is an exceptional clinical-stage biopharmaceutical company active in the discovery and development of T cells redirecting cancer immunotherapies. We use these powerful T cells to develop groundbreaking immunotherapies that target cancer cells. We are dedicated to transforming cancer treatment and improving patient outcomes through cutting-edge research and advanced TCR technology.

Why Join Us?
  • Innovative Environment: Help to pioneer advancements in cancer immunotherapy.
  • Collaborative Culture: Be part of a diverse team dedicated to your professional growth.
  • Global Impact: Contribute to therapies that make a lasting impact on patients globally.

We are seeking an Associate Manager to support our Precision Medicine & Biomarkers team. The Associate Manager will support the day-to-day functioning of a CLIA/CAP-accredited clinical laboratory, ensuring timely and compliant execution of biomarker assays for clinical trials. This role combines technical oversight, personnel management, and process optimization to maintain high-quality testing standards and operational efficiency.

FLSA Classification: Salary, Exempt
Schedule: 8:00 AM – 5:00 PM; Monday to Friday; On-site
Reports to: Associate Director, Precision Medicine & Biomarkers
Location: 13203 Murphy Road Suite 100 Stafford, TX 77477

What You’ll Do:
As an Associate Manager, you will play a key role in:
Laboratory Operations and Compliance:
  • Support biomarker testing for Immatics clinical trials in a timely and compliant manner.
  • Train and maintain competency in key biomarker assays.
  • Supervise daily operations to ensure compliance with CLIA and CAP regulations.
  • Collaborate with the quality team to implement and monitor quality control measures to ensure accurate and timely test results.
  • Participate in internal and external audits and proficiency testing to uphold regulatory and accreditation standards.
  • Prepare for regulatory inspections through regular gap assessments and process improvements.
  • Act as floor manager to monitor day-to-day laboratory activity, ensuring staff are working efficiently and workflows are optimized.
  • Assist with scheduling daily and weekly lab activities, ensuring timely execution and adjusting plans as needed to maintain throughput.
  • Provide oversight of sample handling workflows, including coordination of all clinical samples, blood samples for CTC (circulating tumor cell) processing, TCERquant and RNAseq Samples.
  • Maintain clear oversight of lab personnel schedules, ensuring coverage and operational continuity.
Team Leadership and Development:
  • Cultivate a collaborative team culture built on trust and open communication.
  • Recruit, onboard, and align staff with lab objectives and culture.
  • Support training and onboarding of new personnel, ensuring competency in lab procedures, equipment use, and documentation standards.
  • Provide timely feedback, coaching, and performance management to support professional growth.
  • Recognize individual and team contributions while constructively addressing performance challenges.
Technical Expertise on Molecular Biology Assays:
  • Train staff on molecular techniques, including nucleic acid extractions, qPCR assays, dPCR, and immunohistochemistry, ensuring proper documentation.
  • Support drafting and revision of standard operating procedures (SOPs) and laboratory manuals.
  • Assist R&D activities by planning and execution of assay verification and validation experiments.
  • Collaborate cross-functionally with R&D, Clinical Operations, Bioinformatics, and other departments to ensure seamless lab operations.
Data Management and Collaboration:
  • Oversee database management for accurate storage and retrieval of experimental data.
  • Work closely with internal and external teams to facilitate seamless project coordination.
  • Maintain equipment and manage related contracts, purchases, and budgeting processes.

Secondary Functions:
  • Attend organizational meetings.
  • Assist in CLIA/CAP inspection activities.
  • Attend clinical laboratory related continuing education webinars/ courses.
  • Other duties as assigned.

Required Experience and Education:
  • Bachelor’s or Master’s degree in biology, Molecular Biology, Biochemistry, or a related scientific discipline.
  • Minimum of 5 years of experience in a clinical, CLIA-regulated laboratory.
  • Strong knowledge of molecular diagnostic methods (e.g., nucleic acid extraction, qPCR, dPCR) and their application in clinical testing.
  • Demonstrated ability to lead teams, manage schedules, and resolve workflow bottlenecks.
Preferred Experience and Education:
  • Direct experience with CLIA/CAP audits or inspections, including inspection readiness activities.
  • Proficiency in assay development, validation, and implementation, ideally within a clinical laboratory context.
  • Working knowledge of laboratory information management systems (LIMS) and data handling in a regulated setting.
  • Experience with handling human clinical samples, including whole blood, FFPE tissues, and RNA/DNA extracts.
  • Familiarity with project management principles or laboratory operational metrics.
  • Experience with training and onboarding technical staff in a clinical or research laboratory environment.
  • Certification or continuing education in clinical laboratory science, quality systems, or laboratory management is a plus
Competencies:
  • Leadership
  • Attention to Detail
  • Time Management
  • Problem Solving
  • Communication
  • Initiative
  • Compliance
Work Environment:
This position works in a typical office and/or clinical lab environment with moderate noise levels and uses phone, computer, office equipment and supplies on a regular basis. While performing the duties of this job, the employee is occasionally exposed to moving mechanical parts, fumes or airborne particles, pathogens and toxic or caustic chemicals. The employee is occasionally exposed to wet and/or humid conditions, risk of electrical shock, sharps, or cuts, while performing tests.

Physical demands:
  • Communicating Verbally – expressing or exchanging ideas by means of the spoken word to impart oral information to others to convey detailed spoken instructions or other workers accurately, loudly or quickly.
  • Hearing – the ability to hear, understand, and distinguish speech and/or other sounds one-on-one, group or conference, telephone, and other sounds.
  • Keyboarding – entering data or text into a computer or other machine by means of a keyboard. Devices include a traditional keyboard, 10 key-pad, touch screens and others.
  • Lifting - raising or lowering an object (up to 25 lbs) from one level to another (includes upward pulling). Carrying is to transport an object – usually by holding it in the hands or arms but may occur on the shoulder.
  • Near Visual Acuity – clarity of vision at approximately 20 inches or less (working with small objects, reading small print, including the use of computers).
  • Pushing - Exerting force upon an object so that the object moves away from the object.
  • Pulling - Exerting force upon an object so that the object moves toward the force.
  • Sitting – remaining in a sitting position for at least 50% of the time.
  • Standing/Walking - remain on one's feet in an upright position at a workstation.
  • Stooping – occasional bending the body downward and forward by bending the spine at the waist - requiring full use of the lower extremities and back muscles.

Work authorization/security clearance requirements :

Legal eligibility to work in the United States is required. Immatics participates in E-Verify and all new employees will be subject to the Department of Homeland Security requirements for employment

Affirmative Action/EEO statement:

Immatics is an equal opportunity employer. All employment decisions including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs.

What do we offer?

At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can expect if you join Immatics

Comprehensive Benefits:
  • Competitive rates for Health, Dental, and Vision Insurance
  • 4 weeks of Paid Time off, granted up front each year and prorated for first and last year of employment.
  • Sick Time Off – 56 hours
  • 12 Paid Holidays
  • 100% Employer-Paid Life Insurance up to at 1x annual salary, up to 100K ( club together)
  • 100% Employer Paid Short- and Long-Term Disability Coverage
  • 401(k) with Immediate Eligibility & company match…
  • You are eligible for 401(k) plan participation as of your first paycheck.
  • The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.
  • Partially paid Parental Leave for eligible employees. (3 weeks)
  • Additional voluntary employee paid coverages including Accident, Hospital Indemnity, and Critical Illness Employee Paid Identity Theft Protection and Pet Insurance.

Professional Growth:
  • Opportunities to work with leading experts in the field of T-cell immunotherapy.
  • Company provided learning and development opportunities
  • Fast paced, high demand collaborative and dynamic environment.

Interested in this job?

Apply now

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