Senior Research Scientist - Endocrine Neoplasia & HD
MD Anderson
Houston, TX 77030
$78,500 - $117,500 a year
Description
Cancers of endocrine glands are rare, but their optimal treatment requires the same attentive diagnosis and therapy as more common malignancies. MD Anderson's Endocrine Neoplasia and Hormonal Disorders department provides comprehensive diagnostic and treatment services for patients with endocrine system tumors, both malignant and benign. Here's just a partial list of diseases treated by our physicians, nurses and other caregivers.
This is a part time, benefits eligible position working, Monday-Friday from 08am-1:30pm, maximum weekly hours, 28.
The ideal candidate is an independent and highly motivated researcher with extensive experience in basic and translational biomedical research, particularly in spermatogonial stem cell biology using mouse and rhesus monkey models. This individual demonstrates strong initiative in experimental design, execution, data analysis, and interpretation, with deep expertise in cell signaling pathways and molecular and cellular techniques including viral gene transfection, qRT-PCR, microarrays, immunoblotting, flow cytometry, ChIP, tissue culture, IHC/IF (confocal microscopy preferred), and next-generation sequencing analysis.
The candidate has hands-on experience with mouse xenografts, genetically engineered cancer models, animal gavage and drug treatments, testicular surgery, stem cell transplantation, and biopsy procedures, and possesses a strong foundation in biostatistics and experimental design. They are proficient in independently drafting manuscripts, contributing to grants, maintaining rigorous experimental records, and presenting findings to scientific audiences. In addition, the ideal candidate functions as a scientific and technical leader within the laboratory-mentoring and training students and staff, developing and maintaining SOPs, ensuring regulatory compliance (IACUC/IBC), overseeing lab safety and operations, and actively learning new techniques to advance research objectives while upholding the highest standards of scientific integrity.
Research Duties
General Laboratory Duties
Training Duties
Other Duties as Assigned
EDUCATION
WORK EXPERIENCE
The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition.
This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment.
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state, or local laws unless such distinction is required by law.http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html
Additional Information
#LI-Onsite
This is a part time, benefits eligible position working, Monday-Friday from 08am-1:30pm, maximum weekly hours, 28.
The ideal candidate is an independent and highly motivated researcher with extensive experience in basic and translational biomedical research, particularly in spermatogonial stem cell biology using mouse and rhesus monkey models. This individual demonstrates strong initiative in experimental design, execution, data analysis, and interpretation, with deep expertise in cell signaling pathways and molecular and cellular techniques including viral gene transfection, qRT-PCR, microarrays, immunoblotting, flow cytometry, ChIP, tissue culture, IHC/IF (confocal microscopy preferred), and next-generation sequencing analysis.
The candidate has hands-on experience with mouse xenografts, genetically engineered cancer models, animal gavage and drug treatments, testicular surgery, stem cell transplantation, and biopsy procedures, and possesses a strong foundation in biostatistics and experimental design. They are proficient in independently drafting manuscripts, contributing to grants, maintaining rigorous experimental records, and presenting findings to scientific audiences. In addition, the ideal candidate functions as a scientific and technical leader within the laboratory-mentoring and training students and staff, developing and maintaining SOPs, ensuring regulatory compliance (IACUC/IBC), overseeing lab safety and operations, and actively learning new techniques to advance research objectives while upholding the highest standards of scientific integrity.
Research Duties
- Demonstrates considerable initiative in planning and executing experiments and in evaluating and interpreting results.
- Conducts basic and translational research focused on the regulation of growth, differentiation, and survival of spermatogonial stem cells in mouse and rhesus monkey models, including the cellular and molecular effects of chemotherapeutic agents.
- Demonstrates a strong understanding of cell signaling pathways.
- Applies technical expertise in gene transfection using viral vectors and analysis of gene expression via qRT-PCR, microarrays, immunoblotting, flow cytometry, chromatin immunoprecipitation, and tissue culture.
- Has experience with mouse xenografts, genetically engineered animal models of cancer, and animal gavage and drug treatments.
- Performs testicular surgery and stem cell transplantation in mice and rhesus monkeys.
- Conducts testicular biopsy procedures and handles tissue samples appropriately.
- Performs IHC and IF imaging; experience with confocal microscopy is preferred.
- Analyzes and interprets next-generation sequencing datasets (preferred).
- Independently drafts manuscripts without supervision.
- Possesses strong knowledge of statistical methods used in biological and medical animal studies, including experimental design principles such as power analysis, randomization, ANOVA, regression models, and the appropriate selection of parametric and non-parametric tests.
- Functions independently in the development and initiation of research projects; mentors laboratory personnel as required; develops techniques; maintains standard operating procedures; and ensures the quality and integrity of research procedures.
- Contributes to grant preparation and manuscript publication.
- Provides scientific expertise, knowledge, and technical insight to address research problems.
- Compiles, writes, and submits project results to the principal investigator and presents data to professional groups.
- Performs experiments as directed by the principal investigator within specified timeframes.
- Maintains clear and accurate records of all experimental work performed.
- Learns new skills to enhance and advance research projects.
- Complies with all institutional policies, procedures, and standards.
General Laboratory Duties
- Maintains and ensures laboratory safety, including working knowledge of laboratory equipment and monitoring proper use.
- Monitors and maintains tissue culture supplies and the tissue culture station for efficient operation.
- Attends required laboratory safety training and handles chemicals and reagents in accordance with safety guidelines.
- Maintains accurate animal surgery records and scientific protocols, including IACUC and IBC documentation.
- Ensures a clean, organized, and safe laboratory environment.
Training Duties
- Selects key classified personnel; assigns and reviews subordinate work; establishes specific goals and objectives; evaluates resulting research data; and revises techniques or approaches as needed.
- Plans and supervises the training of students, technicians, and other laboratory personnel in proper laboratory techniques, equipment use, and safety procedures, including initial training in qPCR, IHC, IF, tissue culture techniques, and biosafety.
- Trains and supervises students, technicians, and staff in current scientific protocols and in the proper operation of required laboratory equipment.
Other Duties as Assigned
- Perform other duties as required
EDUCATION
- Required: Master's Degree Natural sciences or related field.
- Preferred: PhD Natural sciences.
- Preferred: Medical Degree
WORK EXPERIENCE
- Required: 6 years Experimental or scientific work experience, or
- Required: 3 years Experimental or scientific work experience with PhD or medical degree.
The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition.
This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment.
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state, or local laws unless such distinction is required by law.http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html
Additional Information
- Requisition ID: 179597
- Employment Status: Part-Time Benefits Eligible
- Employee Status: Regular
- Work Week: Days
- Minimum Salary: US Dollar (USD) 78,500
- Midpoint Salary: US Dollar (USD) 98,000
- Maximum Salary : US Dollar (USD) 117,500
- FLSA: exempt and not eligible for overtime pay
- Fund Type: Soft
- Work Location: Onsite
- Pivotal Position: No
- Referral Bonus Available?: No
- Relocation Assistance Available?: No
#LI-Onsite